OBJECTIVE Erlenmeyer flask deformity is a common radiological finding in patients with Gaucher's disease; however, no definition of this deformity exists and the reported prevalence of the deformity … ERLENMEYER FLASK DEFORMITY (A SHORT REVIEW AND DIFFERENTIAL DIAGNOSIS) Radiology Classroom. Corning disposable Erlenmeyer flasks are sterile, ready to use, and ideal for shaker culture applications and storage. A classical Erlenmeyer deformity. German organic chemist. Erlenmeyer, Emil Born June 28, 1825, in Wehen, near Wiesbaden; died Jan. 22, 1909, in Aschaffenburg. Improving the quantitative classification of Erlenmeyer flask deformities Skeletal Radiology , Jul 2020 Gautam Adusumilli , Joshua D. Kaggie , Simona D’Amore , Timothy M. Cox , Patrick Deegan , James W. MacKay , Scott McDonald Unable to process the form. The Erlenmeyer flask deformity is a common skeletal modeling deformity, but current classification systems are binary and may restrict its utility as a predictor of associated skeletal conditions. The deformity consists of lack of modeling of the di‐metaphysis with abnormal cortical thinning and lack of the concave di‐metaphyseal curve resulting in an Erlenmeyer flask‐like appearance. Hereditary multiple exostoses (shown above): Due to sessile lesions. Oct. 14, 2020. Osteopetrosis: Niemann-Pick disease: Gaucher disease: Flask deformity due to impaired remodeling of the metaphyses of tubular … The presence of Erlenmeyer flask deformity implies involvement in childhood when the skeleton is developing and is an important diagnostic indicator of disease. M95.8 is a billable codeused to specify a medical diagnosis of other specified acquired deformities of musculoskeletal system. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. ADVERTISEMENT: Supporters see fewer/no ads, Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. A student of J. von Liebig’s, Erlenmeyer graduated from the University of Giessen in 1851. The Erlenmeyer flask deformity is a common skeletal modeling deformity, but current classification systems are binary and may restrict its utility as a predictor of associated skeletal conditions. OBJECTIVE: Erlenmeyer flask deformity is a common radiological finding in patients with Gaucher's disease; however, no definition of this deformity exists and the reported prevalence of the deformity varies widely. A: achondroplasia; P: Pyle disease (metaphseal dysplasia) and craniometaphyseal dysplasias; O: osteopetrosis, osteochondromatosis; F: fibrous dysplasia; D: down syndrome; R: rheumatoid arthritis, rickets An Erlenmeyer flask, also known as a conical flask (British English) or a titration flask, is a type of laboratory flask which features a flat bottom, a conical body, and a cylindrical neck. Erlenmeyer flask bone deformity (EFD) is a long-standing term used to describe a specific abnormality of the distal femora. Check for errors and try again. Fig. Balkissoon AR, Hayes CW. 86 (1030): 20130398. deformity of the femurs Erlenmeyer flask shaped thighbone 0004975 Osteopetrosis Harder, denser, fracture-prone bones 0011002 Showing of 4 Last updated: 5/1/2019 Making a [rarediseases.info.nih.gov] Distal end of the femur exhibited absence of normal contour and presented with flask shaped enlargement termed as " Erlenmeyer flask deformity " [Figure 8]. 3 (January 1860), 21-22. It is one of the most common flasks used within laboratories. ; Hereditary multiple exostoses (shown above): Due to sessile lesions. It has been classically used with reference to the distal ends of the femora, however it is also seen in the proximal humeri, tibiae, and the distal radii and ulnae . A quantifiable 3-point system of severity classification … 3. Some of the causes of an Erlenmeyer flask deformity can be recalled with the following mnemonics: AP OF DR GHLN; CHONG; Lead GNOME; APC(de)FGH; Mnemonics AP OF DR GHLN. The causes can also be remembered with the mnemonics AP OF DR GHLN, CHONG or Lead GNOME. (2013) The British journal of radiology. Erlenmeyer flask bone deformity (EFD) is a long-standing term used to describe a specific abnormality of the distal femora. The following article is from The Great Soviet Encyclopedia (1979). Blog. 1. An Erlenmeyer flask is used for the storing and mixing of chemicals in a laboratory setting. The Erlenmeyer flask deformity is a common skeletal modeling deformity, but current classification systems are binary and may restrict its utility as a predictor of associated skeletal conditions. Erlenmeyer flask - shaped so that its liquid content can be shaken laterally without spilling. Yesterday at 6:00 PM. ty. The frequency of the Erlenmeyer flask deformity in Gaucher9s disease has been reported to be between 44% and 61% of patients [8–10]. Radiology Classroom. Mosby Inc. (2007) ISBN:0323040683. Osteochondrodysplasia is a general term for a disorder of the development (dysplasia) of bone ("osteo") and cartilage ("chondro"). The Erlenmeyer flask deformity refers to the flaring of metaphyses of tubular bones and can be seen with: Chronic anemia: Hemoglobinopathies such as Thalassemia and sickle cell disease. hypertrichotic osteochondrodysplasia (Cantu syndrome), multicentric fibromatosis with metaphyseal dysplasia, osteopetrosis with renal tubular acidosis. Talk to our Chatbot to narrow down your search. {"url":"/signup-modal-props.json?lang=us\u0026email="}. Case 14: intramedullary osteosclerosis. Faden MA, Krakow D, Ezgu F, Rimoin DL, Lachman RS. Erlenmeyer Flask Deformity of the Femur Symptom Checker: Possible causes include Autosomal Recessive Osteopetrosis Type 6. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. Tips to keep in mind for World Mental Health Day Note the diffuse bone marrow infiltration and intact femoral heads, ruling out osteonecrosis as a possible cause of pain. Three ROIs were drawn for each femur: physis to 2 cm above the physis, 2 cm to 4 cm above the physis, and 4 cm to 6 cm above the physis. The deformity consists of lack of modeling of the di-metaphysis with abnormal cortical thinning and lack of the concave di-metaphyseal curve resulting in an Erlenmeyer flask-like appearance. Note that each femur has a different degree of metaphyseal flaring. 1999;212 (3): 708-10. The characteristic Erlenmeyer flask deformity with no changes in the skull radiograph would narrow down the diagnosis to Pyle's dysplasia. 4. Check for errors and try again. When the enzyme is defective, glucocerebroside accumulates, particularly in … 149A (6): 1334-45. Check the full list of possible causes and conditions now! A, T 2-weighted MRI image of both femurs giving the typical appearance of Erlenmeyer flask deformity (arrows). It is named after the German chemist Emil Erlenmeyer (1825–1909), who created it in 1860. {"url":"/signup-modal-props.json?lang=us\u0026email="}. Osteopetrosis: The ICD-10-CM code M95.8 might also be used to specify conditions or terms like abnormal prominence of clavicle, abnormal prominence of scapula, acquired deformity of abdomen, acquired deformity of abdominal wall, acquired deformity of clavicle, acquired deformity of scapula, etc Weissleder R, Wittenberg J, Harisinghani MG. Primer of diagnostic imaging. The left image is a femur rated “No EFD”, the center “Mild It has been classically used with reference to the distal ends of the femora, however it is also seen in the proximal humeri, tibiae, and the distal radii and ulnae 4. (2009) American journal of medical genetics. n. A conical laboratory flask … ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. Multimodality imaging features of hereditary multiple exostoses. The name refers to the resemblance to a flat bottomed titration flask used by chemists, (known as a conical flask in British English.). Erlenmeyer flask deformity (EFD) (also known as metaphyseal flaring) refers to a radiographic appearance typically on a femoral radiograph demonstrating relative constriction of the diaphysis and flaring of the metaphysis.. Erlenmeyer flask synonyms, Erlenmeyer flask pronunciation, Erlenmeyer flask translation, English dictionary definition of Erlenmeyer flask. Radiology. The disorder is characterized by bruising, fatigue, anemia, low blood platelet count and enlargement of the liver and spleen, and is caused by a hereditary deficiency of the enzyme glucocerebrosidase(also known as glucosylceramidase), which acts on glucocerebroside. 1. All of our disposable Erlenmeyer flasks feature molded in graduations for accuracy, are certified nonpyrogenic, are individually packaged, and come with a vent cap option for continuous gas exchange while maintaining sterility and preventing leakage. January 6 at 5:55 PM. Unable to process the form. 2. Emil Erlenmeyer, "Zur chemischen und pharmazeutischen Technik," Zeitschrift für Chemie und Pharmacie, vol. Erlenmeyer flask deformity (EFD) (also known as metaphyseal flaring) refers to a radiographic appearance typically on a femoral radiograph demonstrating relative constriction of the diaphysis and flaring of the metaphysis. The conically-shaped flask with a wide base and short narrow neck was created by the German chemist Emil Erlenmeyer (1825–1909) in 1860 3. REVERSE RIM SIGN. B, An Erlenmeyer flask. However, since there is no rigorous Erlenmeyer flask bone deformity (EFD) is a long‐standing term used to describe a specific abnormality of the distal femora. SCLEROSING BONE DYSPLASIAS (A QUICK REVIEW) IMPORTANT DIFFERENTIAL DIAGNOSIS TO LEARN. The third group was EFD-marrow expansion type (EFD-ME) in which bone marrow hyperplasia or infiltration leads to abnormal modeling (e.g., Gaucher disease). 1 Distal femur ROIs to capture the Erlenmeyer flask deformity. Erlenmeyer flask bone deformity (EFD) is a long‐standing term used to describe a specific abnormality of the distal femora. Gaucher's disease or Gaucher disease (GD) is a genetic disorder in which glucocerebroside (a sphingolipid, also known as glucosylceramide) accumulates in cells and certain organs. The Erlenmeyer flask was created by Emil Erlenmeyer in the 1860s to help scientists have a better way of mixing, pouring and storing chemicals. The Erlenmeyer flask, also known as a titration or conical flask, is probably the most iconic … The deformity consists of lack of modeling of the di-metaphysis with abnormal cortical thinning and lack of the concave di-metaphyseal curve resulting in an Erlenmeyer flask-like appearance. Objective: Erlenmeyer flask deformity is a common radiological finding in patients with Gaucher′s disease; however, no definition of this deformity exists and the reported prevalence of the deformity varies widely. Some of the causes of an Erlenmeyer flask deformity can be recalled with the following mnemonics: ADVERTISEMENT: Supporters see fewer/no ads, Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Part A. It might be outdated or ideologically biased. A quantifiable 3-point system of severity classification … Video conferencing best practices: Tips to make meeting online even better; Oct. 8, 2020. Kok HK, Fitzgerald L, Campbell N, Lyburn ID, Munk PL, Buckley O, Torreggiani WC. The Erlenmeyer flask deformity is a common skeletal modeling deformity, but current classification systems are binary and may restrict its utility as a predictor of associated skeletal conditions. Erlenmeyer flask deformity - a deformity at the distal end of the femur with the result that the bone is wide for a much longer distance up the shaft than normal. The Erlenmeyer flask bone deformity in the skeletal dysplasias. Patients with anaemia and heavy metal poisoning commonly have irregular transverse radiodense lines near the ends of the long bones, which is however not specific. ( er'lĕn-mī-ĕr ), a deformity at the distal end of the femur caused by a failure of the shaft of the bone to develop to its normal tubular shape, with the result that the bone is wide for a much longer distance up the shaft than normal; encountered in … Erlenmeyer flask deformity (EFD), also known as metaphyseal flaring, refers to a radiographic appearance typically on a femoral radiograph demonstrating relatively reduced constriction of the diaphysis and flaring of the metaphysis as a result of undertubulation. The Erlenmeyer flask deformity refers to the flaring of metaphyses of tubular bones and can be seen with: Chronic anemia: Hemoglobinopathies such as thalassemia and sickle cell disease. Erlenmeyer flask bone deformity (EFD) is a long-standing term used to describe a specific abnormality of the distal femora. Of the femur Symptom Checker: possible causes and conditions now 22, 1909, in.. 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